EBSA16 Preconference Courses 2013

2-day course, Monday and Tuesday, 17 and 18 June 2013

A) Auditing: a comprehensive and practical introduction (limited to 12 participants)


Helmut Bachmayer, Biosafety & Biosecurity Consultant, Maria Enzersdorf/A<
Gary Burns, Biosafety & Biosecurity Consultant, Congleton/UK

This two day practical course provides a comprehensive and sound practical introduction to auditing. The course takes participants through the principles, recognized best practices and essential techniques of (HSE / biosafety) auditing. It provides them with guidance on planning and performing of an audit in line with international standards. The course will combine elements previously covered in the one day EBSA pre-conference courses "Biosafety audits and inspections - a basic course" and "Auditing - beyond the basics". Newly introduced feature will include the opportunity for delegates to take part in a "mock audit" of a laboratory facility.

The course will be of interest to those with no or limited auditing experience and / or formal training. It will set out the principles of effective (bio)safety, health and environmental auditing and compare and contrast this with inspection approaches. The trainers will explain how to prepare, structure and conduct an audit by sharing with the participants their extensive auditing experience in the areas of HSE / biosafety. They will point out potential pitfalls as well as good practices including communication and interviewing skills, and drafting of audit reports. The course will be highly interactive and practical with focus on syndicate work in break-out sessions and exercises including simulation of audit opening and closing sessions, interviewing as part of desk-top reviews and facility walk-throughs, and drafting of an audit report.

At the end of the two day training course participants will understand the elements of an audit system and programme, they will know the essential tools and realize behavioural implications. The course should enable participants to plan and carry out audits of small facilities within the context of their own work experience, and to contribute to the planning of as well as participate as a team member in HSE / biosafety audits of a more complex nature lead by an experienced auditor.

 The class size is limited to 12 participants to ensure productive interactions (syndicate work in break-out sessions and plenary discussions).

 2-day course, Monday and Tuesday, 17 and 18 June 2013

B) Emergency preparedness and response & incident and accident investigation


Walter Kempenaers, Perseus BVBA, Zwijnaarde/B
Patrick Rüdelsheim, Perseus BVBA Zwijnaarde/B

From minor lab mishaps to large accidents, biosafety professionals have a pivotal role in minimizing unwanted effects of biological agents when normal biosafety or biosecurity operational controls fail.

The course introduces participants to emergency management and its key components (preparedness, response, contingency, crisis management, recovery and investigation). Assessment of credible emergency scenarios and integration of bio-risks in emergency plans should enable an organization to prepare (actors, infrastructure & equipment, procedures, business continuity and communication) for a reasonable response proportionate to the scale and nature of the emergency. Effective testing, communication and training approaches, including emergency exercises and simulations, will be discussed.

In the second part of the training, an introduction on how to set up an incident investigation process will be provided. Root cause analysis techniques and how they lead to corrective and preventive actions will be demonstrated.

Definitions, references and background information, will be complemented with examples on how a biosafety professional can prepare for such events, respond, keep records and identify effective corrective actions. Participants will be able to practice the introduced tools on case studies covering minor as well as major emergency situations involving biological material. On this basis the participants shall be able to develop an emergency management plan, advise on its implementation and conduct an incident investigation.

2-day course, Monday and Tuesday, 17 and 18 June 2013

C) BSL3 hands-on (limited to 8 participants) 2-days course


Kathrin Summermatter, IVI, Mittelhäusern/CH
Daniel Kümin, SPIEZ LABORATORY, Spiez/CH

This two day course will introduce participants to the basics of working safely in a BSL3 laboratory. The course content was adapted from the BSL3 biosafety course of the Swiss Biosafety Curriculum. Participants will perform risk assessments, learn more about BSL3 design and engineering, get introduced to BSL3 specific PPE and use it, cover aspects of waste management and room fumigation, exercise using safety equipment under BSL3 conditions and go through different emergency scenarios amongst other things. The focus of the course lies clearly on practical exercises which limits the number of people who may attend to 8. This is a very intense course that will ask a lot from participants.

Please keep in mind that the course will take place at the Institute of Virology and Immunoprophylaxis (IVI) in Mittelhäusern (near Bern). Also note that due to the very limited amount of time afforded for this subject, course times had to be extended compared to other pre-conference courses taking place in Basel (start 7:45 am, end 5:30 pm).




1-day courses on Tuesday, 18 June 2013

D) Fundamentals of laboratory decontamination


Allan Bennett, Public Health England, Salisbury/UK
Gijsbert Van Willigen, Leiden University Medical Center/NL

Learning outcomes from this course:

• Describe the differences in sterilisation, disinfection and decontamination

• Pros and cons of different chemical disinfectants

• Evaluate disinfection options and applications

• The disinfection database of the Dutch BVF-Platform

• Understand biocide legislation

• Describe options for the gaseous disinfection of labs and cabinets

• Understand physical factors affecting efficacy of different gaseous decontaminants

• Understand limitation of gaseous disinfectants

• Evaluate gaseous disinfectant efficacy against biological agents in different environments

• Understand procedures to carry out safe and effective gaseous decontamination


1-day course on Tuesday, 18 June 2013

E) Training should be fun - techniques and pitfalls


Per Staugaard, Biosafety Training and Consultancy, Utrecht/NL
Vibeke Halkjær-Knudsen, Sandia National Laboratories, Albuquerque NM, USA 

This course is intended for all biosafety professionals involved in training, setting up training programs, choosing training methods and tools, evaluation, assessment and particularly for those, giving training.

After an introduction to training in general, the course will  focus on different training methods and their pro's and con's.

The course is highly interactive and most of the relevant training methods will be actively used / demonstrated during the day.  This is an intense course that will ask a lot from participants.

After this course the participants will have an understanding of which training methods are suitable for what purposes, size of groups and to evaluation of training in general.

At the end of the day, the participants will have the opportunity to draft a personal action plan for setting up a specific training programme for the institution or company the participant belongs to.

1-day course on Tuesday, 18 June 2013

F) Safe and Secure -Introduction to Practical Issues of Biosecurity


Heather Sheeley, Public Health England/UK
Peter Clevestig, SIPRI/S

This short course will introduce the issues and practical approaches to developing and influencing an effective biosecurity programme.

The course will introduce delegates to the issues required to develop an effective biosecurity programme at the institute level. The course includes practical and theoretical aspects to adopt and to determine risk.

Areas covered will be people, assets, legal, physical and information security required to provide a comprehensive, effective and appropriate programme. On concluding this course the participant will be able to: draft a biosecurity plan, hold informed dialogue with key stakeholders, work with other disciplines to implement a biosecurity plan.

Suitable for those

• with biosafety responsibilities who want to broaden their knowledge in this area

• charged with drawing up a biosecurity plan

• those wishing to check the adequacy of their arrangements with others or update knowledge

• regulators and policy makers who need to have an appreciation of the implications at operational level

1-day course on Tuesday, 18 June 2013

G) Biological materials - known and unknown hazards


Dana Brehar-Cioflec, National Institute of Public Health, Timisoara/RO 
Franziska Enderle, University Hospital Zurich/CH

Have you ever been in a situation where you had to deal with biological material and had no clue what kind of pathogens it might contain? Have you wondered whether these specimens were containing higher risk group agents than group 1 or 2. Have you wondered how to keep yourself and your colleagues safe when dealing with these specimens whether in research or diagnostics, specifically when it came to  processing large numbers of samples ?

Connected to the present dynamics in the field of microbiology and epidemiology of infectious diseases new biological agents keep emerging as well as changes occurring in previously known agents exhibiting new features in terms of pathogenicity, virulence and resistance patterns.

In this context, additional or different containment measures, procedures, equipment might have to be developed and best adapted to emerging situations. Furthermore, and very importantly, a best strategy needs to be developed to organize the activity and thus keep the balance between the best quality and timeliness of test results and the best possible protection of both laboratory staff and the environment. Last but not least, consideration has to be given to technical requirements for laboratory equipment to ensure the safe processing of "unknown" specimens and still avoid excessive expenses and possible "overkills" (shooting sparrows with cannonballs).

There are no simple and unique answers to such questions but there is a wide variety of useful information sources and methodology to support biosafety professionals worldwide to adapt and upgrade the activity in their institutions to match these challenges posed by biological hazards.

Lectures will alternate with interactive sessions during which participants are expected to share knowledge and cooperate in formulating relevant questions and proposing solutions according to a defined risk evaluation methodology. The international and European regulations and recommendations will be highlighted and relevant references and links will be provided.

1-day course on Tuesday, 18 June 2013

H) Biosafety in animal facilities - the challenge


Stephane Karlen, EPFL, Lausanne/CH
Uwe Müller-Doblies, Institute of Animal Health, Pirbright/UK


- General considerations: risk assessment, containment systems, occupational health, health monitoring, hygiene, zoonotic risks, waste management

- Small animal biosafety: sourcing and selection of animals, containment of small animals, their safe manipulation (handling, inoculation, force feeding, etc.), different experimental systems (infectious organisms, viral vectors, etc).

- Large animal biosafety: sourcing and selection of animals, waste issues from large animals, necropsy, carcass disposal, personal protective equipment, cleaning and disinfection, facility maintenance.

- PowerPoint presentations, movies, risk assessment exercises

Target audience:
- This is a basic course for biosafety professionals with no or limited experience in animal experimentation, for young researchers or for all interested parties.


1-day course on Tuesday, 18 June 2013

I) Biological waste management - doing it right?


Toon De Kesel, Bayer CropScience, Gent/B 
Jörg Schibel, University of Tübingen/D 

Biological waste originates from human or animal health care, medical and biotech research, laboratories, greenhouses and other facilities. Careful disposal of this type of waste is an integral component of the organization's biorisk management. There is a wide variety of chemical, biological, and radioactive waste materials generated in typical e.g. microbiology, clinical and biotechnology laboratories. Infectious materials and sharps which are not properly managed pose serious health risks to each person who encounters them, whether in the laboratory itself or at some point during the process of removal and transport. Proper handling, packaging, and labeling are important to protect lab workers and assure that the waste will not become a community hazard en route to ultimate disposal. Some wastes associated with biological materials must be disposed of in special ways because they may have been contaminated with infectious organisms or genetically modified agents.

This biosafety course learning objectives include (1) recommend appropriate biological waste handling and disposal measures / routings in accordance with the current legislative requirements; (2) raise awareness of hazards that may be associated with inappropriate management of biological waste; (3) share the practical knowledge and technology of chemical and physical treatment of biological hazardous waste; (4) integrate the management of these issues into an existing biorisk program as part of a biorisk management system.